Oven baked 3-ingredient chicken supreme is one of those dependable old-school casseroles that earns a permanent spot in the dinner rotation because it is simple, comforting, and almost impossible to mess up. It has that classic Midwestern church-supper feel, built from pantry shortcuts that turn into a rich, cozy meal with very little effort, which makes it especially perfect for busy weeknights when you still want something warm and homemade on the table.
This creamy chicken is especially good served over white rice, buttered egg noodles, or mashed potatoes so none of that mushroom sauce goes to waste. For a little balance, add a simple green vegetable like steamed broccoli, green beans, or a crisp side salad, and if you are feeding guests, warm dinner rolls make it feel extra complete.
Oven Baked 3-Ingredient Chicken Supreme
Servings: 4 to 6
Ingredients
4 boneless, skinless chicken breasts
Directions
1. Preheat the oven to 350°F and lightly grease a medium casserole dish or baking dish.
2. Arrange the chicken breasts in a single layer in the prepared baking dish.
3. In a medium bowl, stir together the condensed cream of mushroom soup and sour cream until smooth and fully combined.
4. Spoon the sauce evenly over the chicken breasts, spreading it to cover the tops completely.
5. Bake uncovered for 45 to 55 minutes, or until the chicken is cooked through and the sauce is hot and bubbling around the edges.
6. Let the dish rest for 5 minutes before serving so the sauce can settle slightly.
Variations & Tips
Make it extra savory: If you have a few more minutes, sprinkle the chicken lightly with salt, black pepper, garlic powder, or onion powder before adding the sauce. It is still very much the same easy recipe, but the extra seasoning gives the finished dish a little more depth.
Use chicken tenders: Chicken tenders work well if you want faster cooking time or easier serving for kids. Start checking for doneness around 30 to 35 minutes since smaller pieces cook more quickly than full chicken breasts.
Thin the sauce if needed: Some condensed soups are thicker than others, so if your sauce seems too heavy to spread, stir in 2 to 4 tablespoons of milk before spooning it over the chicken. This helps create a smoother, silkier finish after baking.
Prep ahead for busy nights: You can assemble the dish a few hours in advance, cover it, and refrigerate it until dinner time. When you are ready to bake, let it sit at room temperature for about 15 minutes first so the dish cooks more evenly.
Check doneness the easy way: Chicken breasts can dry out if they stay in the oven too long, so use an instant-read thermometer if you have one. Pull the dish when the thickest part of the chicken reaches 165°F for the best texture.
